adaptor

adaptor
A protein complex associated with coated vesicles. Adaptors have been shown to promote the in vitro assembly of clathrin cages and to bind to the cytoplasmic domains of specific membrane proteins. It has been proposed that adaptors link selected membrane proteins to clathrin causing them to be packaged into a coated vesicle. Two adaptors have been identified (HA-1 and HA-2) ; they are hetero-tetramers composed of two proteins of 100-110 kD, termed adaptins, and two smaller polypeptides of around 50 and 20 kD. The HA-1 subunits are g -adaptin, b \'-adaptin with polypeptides of 50 kD and 17 kD. HA-1 is associated with coated pits formed from the Golgi complex. The HA-2 subunits are a -adaptin, b -adaptin with polypeptides of 47 kD and 20 kD. HA-2 is associated with coated pits formed from the plasma membrane. ( b &’- and b -adaptin are closely related).

Dictionary of molecular biology. 2004.

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  • adaptor — (also adapter) ► NOUN 1) a device for connecting pieces of equipment. 2) Brit. a device for connecting more than one plug at a time or plugs of a non standard type to an electrical socket …   English terms dictionary

  • adaptor — [[t]ədæ̱ptə(r)[/t]] adaptors also adapter 1) N COUNT An adaptor is a special device for connecting electrical equipment to a power supply, or for connecting different pieces of electrical or electronic equipment together. 2) N COUNT The adaptor… …   English dictionary

  • adaptor — adapter UK [əˈdæptə(r)] / US [əˈdæptər] or adaptor UK / US noun [countable] Word forms adapter : singular adapter plural adapters an object that allows you to connect two pieces of equipment of different types or sizes a) British an object that… …   English dictionary

  • adaptor — adapteris statusas T sritis informatika apibrėžtis ↑Aparatinės sąsajos įtaisas siejamų įtaisų signalų parametrams suderinti. Dažniausiai naudojamas išoriniams įtaisams, pavyzdžiui, kompaktinių diskų įtaisui, ↑monitoriui, ↑vairasvirtei prijungti… …   Enciklopedinis kompiuterijos žodynas

  • adaptor hypothesis — adaptor hypothesis. См. адапторная гипотеза. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Adaptor protein — An adaptor protein is a protein which is accessory to main proteins in a signal transduction pathway. These proteins tend to lack any intrinsic enzymatic activity themselves but instead mediate specific protein protein interactions that drive the …   Wikipedia

  • Adaptor hypothesis — The adaptor hypothesis is part of a scheme to explain how information encoded in DNA is used to specify the amino acid sequence of proteins. It was formulated by Francis Crick in the mid 1950s, together with the Central Dogma of Molecular Biology …   Wikipedia

  • adaptor — noun see adapter …   New Collegiate Dictionary

  • adaptor — a·dap·tor (ə dăpʹtər) n. Variant of adapter. * * * …   Universalium

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